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In enzymology, a 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase () is an enzyme that catalyzes the chemical reaction :GDP-beta-L-fucose + 1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R GDP + 1,4-beta-D-galactosyl-(alpha-1,3-L-fucosyl)-N-acetyl-D-glucosaminyl- R Thus, the two substrates of this enzyme are GDP-beta-L-fucose and 1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R. Its 3 products are GDP, 1,4-beta-D-galactosyl-(alpha-1,3-L-fucosyl)-N-acetyl-D-glucosaminyl-, and R. This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R 3-alpha-L-fucosyltransferase. Other names in common use include: *Lewis-negative alpha-3-fucosyltransferase *plasma alpha-3-fucosyltransferase *guanosine diphosphofucose-glucoside alpha1→3-fucosyltransferase *galactoside 3-fucosyltransferase *GDP-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R *3-L-fucosyltransferase *GDP-beta-L-fucose:1,4-beta-D-galactosyl-N-acetyl-D-glucosaminyl-R, and *3-L-fucosyltransferase This enzyme participates in 3 metabolic pathways: glycosphingolipid biosynthesis - neo-lactoseries, glycosphingolipid biosynthesis - globoseries, and glycan structures - biosynthesis 2. == Structural studies == As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes , , and . 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase」の詳細全文を読む スポンサード リンク
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